Article
Differences in the ovine HSP90AA1 gene expression rates caused by two linked polymorphisms at its promoter affect rams sperm DNA fragmentation under environmental heat stress conditions.
PloS one - 1 Jan 2015
Salces-Ortiz Judit, Ramón Manuel, González Carmen, Pérez-Guzmán M Dolores, Garde J Julián, García-Álvarez Olga, Maroto-Morales Alejandro, Calvo Jorge H, Serrano M Magdalena
Abstract excerpt
Heat shock (HS) is one of the best-studied exogenous cellular stresses. Almost all tissues, cell types, metabolic pathways and biochemical reactions are affected in greater or lesser extent by HS. However, there are some especially thermo sensible cellular types such as the mammalian male germ cells. The present study examined the role of three INDELs in conjunction with the -660G/C polymorphism located at the...
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