Article
miR-101 suppresses vascular endothelial growth factor C that inhibits migration and invasion and enhances cisplatin chemosensitivity of bladder cancer cells.
PloS one - 1 Jan 2015
Lei Ye, Li Bin, Tong Shiyu, Qi Lin, Hu Xiheng, Cui Yunbo, Li Zengbo, He Wei, Zu Xiongbing, Wang Zhi, Chen Minfeng
Abstract excerpt
BACKGROUND: The microRNA miR-101 is downregulated in several cancers, including bladder cancer. However, miR-101's role in the invasion, metastasis, and chemosensitivity of bladder cancer cells remains unclear. This study was conducted to determine miR-101's role on the lymphangiogenic molecule vascular endothelial growth factor C (VEGF-C) and their effects upon bladder cancer cell migration, invasion, and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
