Article
Association of the miR-146a, miR-149, miR-196a2, and miR-499 polymorphisms with ischemic stroke and silent brain infarction risk.
Arteriosclerosis, thrombosis, and vascular biology - 1 Feb 2013
Jeon Young Joo, Kim Ok Joon, Kim Su Yeoun, Oh Seung Hun, Oh Doyeun, Kim Ok Jun, Shin Byoung Soo, Kim Nam Keun
Abstract excerpt
OBJECTIVE: MicroRNAs play a role in atherosclerosis-related diseases, such as cerebrovascular or cardiovascular disease. However, the effect of miR-146a, miR-149, miR-196a2, and miR-499 polymorphisms on stroke and silent brain infarction (SBI) susceptibility has not been reported. METHODS AND RESULTS: Using polymerase chain reaction-amplified DNA, microRNA polymorphisms were analyzed in 678 patients with ischemic...
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