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Article

Screening protein isoforms predictive for cancer using immunoaffinity capture and fast LC-MS in PRM mode.

Proteomics. Clinical applications - 1 Aug 2015

Lesur Antoine, Ancheva Lina, Kim Yeoun Jin, Berchem Guy, van Oostrum Jan, Domon Bruno

Abstract excerpt

PURPOSE: We report an immunocapture strategy to extract proteins known to harbor driver mutations for a defined cancer type before the simultaneous assessment of their mutational status by MS. Such a method bypasses the sensitivity and selectivity issues encountered during the analysis of unfract...

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Identifiers

PMID: 25656350
DOI: 10.1002/prca.201400158

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25656350-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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