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Article

Diabetes Induces Aberrant DNA Methylation in the Proximal Tubules of the Kidney

5 Feb 2015

Abstract excerpt

Epigenetic mechanisms may underlie the progression of diabetic kidney disease. Because the kidney is a heterogeneous organ with different cell types, we investigated DNA methylation status of the kidney in a cell type-specific manner. We first identified genes specifically demethylated in the normal proximal tubules obtained from control db/m mice, and next delineated the candidate disease-modifying genes bearing...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 25653098
DOI: 10.1681/asn.2014070665

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