Article
Lung cancer incidence decreases with elevation: evidence for oxygen as an inhaled carcinogen
13 Jan 2015
Abstract excerpt
The level of atmospheric oxygen, a driver of free radical damage and tumorigenesis, decreases sharply with rising elevation. To understand whether ambient oxygen plays a role in human carcinogenesis, we characterized age-adjusted cancer incidence (compiled by the National Cancer Institute from 2005 to 2009) across counties of the elevation-varying Western United States and compared trends displayed by respiratory...
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