Article
Status of leptin in MBCR-ABL p210 positive chronic myeloid leukemia patients before and after imatinib therapy: a conflicting scenario.
Clinical laboratory - 1 Jan 2014
Bansal Piyush, Ghalaut Veena S, Sharma Tarun K, Ghalaut Pratap S, Dokwal Sumit, Ghalaut Ragini, Kulshrestha Manish, Dahiya Kiran
Abstract excerpt
BACKGROUND: Chronic myelogenous leukemia (CML), a myeoloproliferative disorder, is characterized by the presence of the fusion gene BCR-ABL in hematopoietic cells. Leptin, considered a link between cancer and obesity, has been reported to be actively involved in hemopoiesis and pathophysiology of CML. There are few and conflicting reports about the status of serum leptin levels and recently alteration in leptin...
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