Article
The possible role of maternal bonding style and CHRNB2 gene polymorphisms in nicotine dependence and related depressive phenotype.
Progress in neuro-psychopharmacology & biological psychiatry - 3 Jun 2015
Csala Iren, Egervari Luca, Dome Peter, Faludi Gabor, Dome Balazs, Lazary Judit
Abstract excerpt
OBJECTIVES: Neuronal nicotinic acetylcholinergic receptors (nAChR) and especially α4β2 nAChRs are the major targets for cessation medications and also for some promising antidepressant agents. Furthermore, depressive symptoms pose multifacet difficulties during cessation therapy. However, gene encoding for the β2 subunit of nAChRs has been poorly investigated in association with depression. Since both nicotine...
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