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Article

Aged men share the sperm protein PATE1 defect with young asthenozoospermia patients

29 Jan 2015

Abstract excerpt

STUDY QUESTION: Does a defect in the human sperm-located protein prostate and testis expressed 1 (PATE1) exist in both aged men and young asthenozoospermia patients? SUMMARY ANSWER: A defect in sperm PATE1 exists in both aged men and young asthenozoospermia patients, and an antibody against PATE1 can decrease human sperm motility and zona-free hamster oocyte penetration. WHAT IS KNOWN ALREADY: Both aged men and...

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PMID: 25637620
DOI: 10.1093/humrep/dev003

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