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Article

Combined immunodeficiency due to MALT1 mutations, treated by hematopoietic cell transplantation.

Journal of clinical immunology - 1 Feb 2015

Punwani Divya, Wang Haopeng, Chan Alice Y, Cowan Morton J, Mallott Jacob, Sunderam Uma, Mollenauer Marianne, Srinivasan Rajgopal, Brenner Steven E, Mulder Arend, Claas Frans H J, Weiss Arthur, Puck Jennifer M

Abstract excerpt

PURPOSE: A male infant developed generalized rash, intestinal inflammation and severe infections including persistent cytomegalovirus. Family history was negative, T cell receptor excision circles were normal, and engraftment of maternal cells was absent. No defects were found in multiple genes associated with severe combined immunodeficiency. A 9/10 HLA matched unrelated hematopoietic cell transplant (HCT) led...

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Source

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Identifiers

PMID: 25627829
DOI: 10.1007/s10875-014-0125-1
PMCID: PMC4352191

Genes

MALT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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