Article
Pneumococcal wall teichoic acid is required for the pathogenesis of Streptococcus pneumoniae in murine models.
Journal of microbiology (Seoul, Korea) - 1 Feb 2015
Xu Hongmei, Wang Libin, Huang Jian, Zhang Yanqing, Ma Feng, Wang Jianmin, Xu Wenchun, Zhang Xuemei, Yin Yibing, Wu Kaifeng
Abstract excerpt
Pneumococcal asymptomatic colonization of the respiratory tracts is a major risk for invasive pneumococcal disease. We have previously shown that pneumococcal wall teichoic acid (WTA) was involved in pneumococcal infection of sepsis and adherence to epithelial and endothelial cells. In this study, we investigated the contribution of pneumococcal WTA to bacterial colonization and dissemination in murine models....
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