Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Translationally controlled tumor protein induces epithelial to mesenchymal transition and promotes cell migration, invasion and metastasis.

Scientific reports - 27 Jan 2015

Bae Seong-Yeon, Kim Hyun Jung, Lee Kong-Joo, Lee Kyunglim

Abstract excerpt

Translationally controlled tumor protein (TCTP), is a highly conserved protein involved in fundamental processes, such as cell proliferation and growth, tumorigenesis, apoptosis, pluripotency, and cell cycle regulation. TCTP also inhibits Na,K-ATPase whose subunits have been suggested as a marker of epithelial-to-mesenchymal transition (EMT), a crucial step during tumor invasiveness, metastasis and fibrosis. We...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epithelial-Mesenchymal Transition
Share to Glycogen Synthase Kinase 3

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glycogen Synthase Kinase 3 beta

Share to Matrix Metalloproteinase 9

Share to Mechanistic Target of Rapamycin Complex 2

Share to Multiprotein Complexes

Share to TOR Serine-Threonine Kinases

Share to Transplantation, Homologous

Source

Open in PubMed Open full text

Identifiers

PMID: 25622969
DOI: 10.1038/srep08061
PMCID: PMC4306963

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Translationally controlled tumor protein induces epithelial to mesenchymal transition and promotes cell migration, invasion and metastasis.PMID 25622969Read ↗

TCTP promotes epithelial–mesenchymal transition in lung adenocarcinomaSemantic proximity Read ↗

The translationally controlled tumour protein (TCTP)Semantic proximity Read ↗

Gene silencing of translationally controlled tumor protein (TCTP) by siRNA inhibits cell growth and induces apoptosis of human prostate cancer cellsSemantic proximity Read ↗

Active PLK1-driven metastasis is amplified by TGF-β signaling that forms a positive feedback loop in non-small cell lung cancerSemantic proximity Read ↗

Characterization of the Translationally Controlled Tumor Protein (TCTP) Interactome Reveals Novel Binding Partners in Human Cancer CellsSemantic proximity Read ↗

Subcellular proteomics revealed the epithelial-mesenchymal transition phenotype in lung cancer.Semantic proximity Read ↗

Down-regulation of TAK1 inhibits migration and invasion of p-NENs by regulating JNK signaling pathway through interaction with PDZD2Semantic proximity Read ↗

A Potential Role for Exosomal Translationally Controlled Tumor Protein Export in Vascular Remodeling in Pulmonary Arterial Hypertension.Semantic proximity Read ↗

Translationally controlled tumor protein: A protein identified in several nontumoral cells including erythrocytesSemantic proximity Read ↗

Na,K-ATPase subunits as markers for epithelial-mesenchymal transition in cancer and fibrosis.Semantic proximity Read ↗

Overexpression of GP73 promotes cell invasion, migration and metastasis by inducing epithelial-mesenchymal transition in pancreatic cancer.Semantic proximity Read ↗

Membrane Proteins Involved in Epithelial-Mesenchymal Transition and Tumor Invasion: Studies on TMPRSS4 and TM4SF5Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.