Article
Adaptation and possible ancient interspecies introgression in pigs identified by whole-genome sequencing.
Nature genetics - 1 Mar 2015
Ai Huashui, Fang Xiaodong, Yang Bin, Huang Zhiyong, Chen Hao, Mao Likai, Zhang Feng, Zhang Lu, Cui Leilei, He Weiming, Yang Jie, Yao Xiaoming, Zhou Lisheng, Han Lijuan, Li Jing, Sun Silong, Xie Xianhua, Lai Boxian, Su Ying, Lu Yao, Yang Hui, Huang Tao, Deng Wenjiang, Nielsen Rasmus, Ren Jun, Huang Lusheng
Abstract excerpt
Domestic pigs have evolved genetic adaptations to their local environmental conditions, such as cold and hot climates. We sequenced the genomes of 69 pigs from 15 geographically divergent locations in China and detected 41 million variants, of which 21 million were absent from the dbSNP database. In a genome-wide scan, we identified a set of loci that likely have a role in regional adaptations to high- and...
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