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Article

[Update on genetic predisposition to prostate cancer].

Bulletin du cancer - 1 Jan 2015

Cussenot Olivier, Cancel-Tassin Géraldine

Abstract excerpt

Genetic predisposition to prostate cancer rarely corresponds to a high penetrance Mendelian pattern of inheritance. These hereditary forms are specific entities for which mutations in the BRCA2 gene, the HOXB13 gene (variant G84E) or, to a lesser extent BRCA1 gene, must be researched. In contrast, the genetic component of the majority of prostate cancer is polygenic, involving an unfavorable combination of common...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25609482
DOI: 10.1016/j.bulcan.2014.12.007

Genes

BRCA1
BRCA2
HOXB13

Variants

Provenance

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