Article
Female rats selectively bred for high intrinsic aerobic fitness are protected from ovariectomy-associated metabolic dysfunction.
American journal of physiology. Regulatory, integrative and comparative physiology - 15 Mar 2015
Vieira-Potter Victoria J, Padilla Jaume, Park Young-Min, Welly Rebecca J, Scroggins Rebecca J, Britton Steven L, Koch Lauren G, Jenkins Nathan T, Crissey Jacqueline M, Zidon Terese, Morris E Matthew, Meers Grace M E, Thyfault John P
Abstract excerpt
Ovariectomized rodents model human menopause in that they rapidly gain weight, reduce spontaneous physical activity (SPA), and develop metabolic dysfunction, including insulin resistance. How contrasting aerobic fitness levels impacts ovariectomy (OVX)-associated metabolic dysfunction is not known. Female rats selectively bred for high and low intrinsic aerobic fitness [high-capacity runners (HCR) and...
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