Article
Autoregulation and homodimerization are involved in the activation of the plant steroid receptor BRI1.
Developmental cell - 1 Jun 2005
Wang Xuelu, Li Xiaoqing, Meisenhelder Jill, Hunter Tony, Yoshida Shigeo, Asami Tadao, Chory Joanne
Abstract excerpt
The leucine-rich-repeat receptor serine/threonine kinase, BRI1, is a cell-surface receptor for brassinosteroids (BRs), the steroid hormones of plants, yet its activation mechanism is unknown. Here, we report a unique autoregulatory mechanism of BRI1 activation. Removal of BRI1's C terminus leads to a hypersensitive receptor, indicated by suppression of dwarfism of BR-deficient and BR-perception mutants and by...
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