Article
Influences of gestational obesity on associations between genotypes and gene expression levels in offspring following maternal gastrointestinal bypass surgery for obesity.
PloS one - 1 Jan 2015
Guénard Frédéric, Lamontagne Maxime, Bossé Yohan, Deshaies Yves, Cianflone Katherine, Kral John G, Marceau Picard, Vohl Marie-Claude
Abstract excerpt
METHODS: Whole-genome genotyping and gene expression analyses in blood of 22 BMS and 23 AMS offspring from 19 mothers were conducted using Illumina HumanOmni-5-Quad and HumanHT-12 v4 Expression BeadChips, respectively. Using PLINK we analyzed interactions between offspring gene variations and maternal surgical status on offspring gene expression levels. Altered biological functions and pathways were identified...
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