Article
Pharmacodynamic genome-wide association study identifies new responsive loci for glucocorticoid intervention in asthma.
The pharmacogenomics journal - 1 Oct 2015
Wang Y, Tong C, Wang Z, Wang Z, Mauger D, Tantisira K G, Israel E, Szefler S J, Chinchilli V M, Boushey H A, Lazarus S C, Lemanske R F, Wu R
Abstract excerpt
Asthma is a chronic lung disease that has a high prevalence. The therapeutic intervention of this disease can be made more effective if genetic variability in patients' response to medications is implemented. However, a clear picture of the genetic architecture of asthma intervention response remains elusive. We conducted a genome-wide association study (GWAS) to identify drug response-associated genes for...
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