Article
Lentiviral-mediated overexpression of homeobox A4 by human umbilical cord mesenchymal stem cells repairs full-thickness skin defects.
Molecular medicine reports - 1 May 2015
He Ling, Tu Huai-Jun, He Wen-Feng, Guo Ling-Ling, Yu Song-Xia, Li Jie, Wu Qiong, Li Jian
Abstract excerpt
A number of types of stem cells have been shown to be effective in wound repair. In the present study the effect of homeobox A4 (HOXA4) overexpression by human umbilical cord mesenchymal stem cells (hUMSCs) on full‑thickness skin repair was evaluated. Isolated hUMSCs were transfected with a lentivirus expressing HOXA4 and cultured for 21 days. Expression of the epidermal cell‑specific markers, cytokeratins 14 and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.