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Article

Regulation of monocyte/macrophage polarisation by extracellular RNA.

Thrombosis and haemostasis - 1 Mar 2015

Cabrera-Fuentes Hector A, Lopez Mercedes L, McCurdy Sara, Fischer Silvia, Meiler Svenja, Baumer Yvonne, Galuska Sebastian P, Preissner Klaus T, Boisvert William A

Abstract excerpt

Monocytes/macrophages respond to external stimuli with rapid changes in the expression of numerous inflammation-related genes to undergo polarisation towards the M1 (pro-inflammatory) or M2 (anti-inflammatory) phenotype. We have previously shown that, independently of Toll-like receptor activation, extracellular RNA (eRNA) could exert pro-thrombotic and pro-inflammatory properties in the cardiovascular system to...

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Identifiers

PMID: 25589344
DOI: 10.1160/TH14-06-0507
PMCID: PMC4427572

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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