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Comparative Genomics Suggests Primary Homothallism of <i>Pneumocystis</i> Species

14 Jan 2015

Abstract excerpt

UNLABELLED: Pneumocystis species are fungal parasites of mammal lungs showing host specificity. Pneumocystis jirovecii colonizes humans and causes severe pneumonia in immunosuppressed individuals. In the absence of in vitro cultures, the life cycle of these fungi remains poorly known. Sexual reproduction probably occurs, but the system of this process and the mating type (MAT) genes involved are not...

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PMID: 25587012
DOI: 10.1128/mbio.02250-14

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