Article
Cotreatment of hairy cell leukemia and melanoma with the BRAF inhibitor dabrafenib.
Journal of the National Comprehensive Cancer Network : JNCCN - 1 Jan 2015
Blachly James S, Lozanski Gerard, Lucas David M, Grever Michael R, Kendra Kari, Andritsos Leslie A
Abstract excerpt
The activating BRAF mutation p.V600E has been identified in many cancers, including colon and lung adenocarcinomas, papillary thyroid cancer, malignant melanoma, and hairy cell leukemia (HCL). Malignant melanoma and HCL are of particular interest because of both the high proportion of cases harboring the mutation and the dramatic responses to BRAF inhibitor therapy reported in the literature. This report presents...
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