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Article

Sema6A and Mical1 control cell growth and survival of BRAFV600E human melanoma cells.

Oncotarget - 20 Feb 2015

Loria Rossella, Bon Giulia, Perotti Valentina, Gallo Enzo, Bersani Ilaria, Baldassari Paola, Porru Manuela, Leonetti Carlo, Di Carlo Selene, Visca Paolo, Brizzi Maria Felice, Anichini Andrea, Mortarini Roberta, Falcioni Rita

Abstract excerpt

We used whole genome microarray analysis to identify potential candidate genes with differential expression in BRAFV600E vs NRASQ61R melanoma cells. We selected, for comparison, a peculiar model based on melanoma clones, isolated from a single tumor characterized by mutually exclusive expression of BRAFV600E and NRASQ61R in different cells. This effort led us to identify two genes, SEMA6A and MICAL1, highly...

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Identifiers

PMID: 25576923
DOI: 10.18632/oncotarget.2995
PMCID: PMC4413617

Genes

BRAF
MICAL1
NRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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