Article
Relationships between IL-6 gene polymorphism, low BMD and periodontitis in postmenopausal women.
Archives of oral biology - 1 Apr 2015
Hanai Y, Sugita N, Wang Y, Yoshihara A, Iwasaki M, Miyazaki H, Nakamura K, Yoshie H
Abstract excerpt
OBJECTIVE: IL-6 plays critical roles in bone resorption and the pathogenesis of periodontitis in both inflammation and alveolar bone loss. A negative correlation was observed between periodontitis and truncal bone mineral density (BMD) in postmenopausal women. The C allele carriers of a genetic polymorphism IL-6-572G/C have higher levels of serum IL-6 compared to G allele carriers. We investigated the possible...
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