Article
Lower prevalence of drug resistance mutations at first-line virological failure to first-line therapy with atripla vs. tenofovir + emtricitabine/lamivudine + efavirenz administered on a multiple tablet therapy.
AIDS (London, England) - 13 Nov 2014
Blanco José L, Montaner Julio S G, Marconi Vincent C, Santoro Maria M, Campos-Loza Ariel E, Shafer Robert W, Miller Michael D, Paredes Roger, Harrigan Richard, Nguyen Mihn L, Perno Carlo F, Gonzalez-Hernandez Lucero A, Gatell José M
Abstract excerpt
BACKGROUND: Fixed-dose combination antiretroviral therapy administered as a single-tablet regimen (STR) may improve virologic suppression rates. The effect of STRs on development of resistance when virologic failure occurs on STRs is not known. OBJECTIVES: To compare the rate of emergent drug resistance mutations (DRMs) on first-line therapy with coformulated tenofovir disoproxil fumarate (TDF)/emtricitabine...
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