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RNA-sequencing analysis of Trichophyton rubrumtranscriptome in response to sublethal doses of acriflavine

1 Oct 2014

Abstract excerpt

BACKGROUND: The dermatophyte Trichophyton rubrum is an anthropophilic filamentous fungus that infects keratinized tissues and is the most common etiologic agent isolated in human dermatophytoses. The clinical treatment of these infections is challenging because only few antifungal drugs are commercially available. To understand the mode of action of cytotoxic drugs against fungi, we evaluated the time-dependent...

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PMID: 25573029
DOI: 10.1186/1471-2164-15-s7-s1

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