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Article

TLR8 gene polymorphism and association in bacterial load in southern Punjab of Pakistan: an association study with pulmonary tuberculosis.

International journal of immunogenetics - 1 Feb 2015

Bukhari M, Aslam M A, Khan A, Iram Q, Akbar A, Naz A G, Ahmad S, Ahmad M M, Ashfaq U A, Aziz H, Ali M

Abstract excerpt

Only 5-10% of people infected with Mycobacterium tuberculosis develop active tuberculosis which suggests a role of genetic variation in host immunity. Genetic variants in TLRs are potential indicator for host susceptibility and outcome of several diseases. We explored the association of nonsynonymous genetic variants (Met1Val) with Toll-like receptor 8 in Pakistani population. Genotypic and allelic distribution...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25572425
DOI: 10.1111/iji.12170

Genes

TLR8

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