Adiponectin as a link between type 2 diabetes and vascular NADPH oxidase activity in the human arterial wall: the regulatory role of perivascular adipose tissue.

doi:10.2337/db14-1011

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Adiponectin as a link between type 2 diabetes and vascular NADPH oxidase activity in the human arterial wall: the regulatory role of perivascular adipose tissue.

Diabetes - 1 Jun 2015

Antonopoulos Alexios S, Margaritis Marios, Coutinho Patricia, Shirodaria Cheerag, Psarros Costas, Herdman Laura, Sanna Fabio, De Silva Ravi, Petrou Mario, Sayeed Rana, Krasopoulos George, Lee Regent, Digby Janet, Reilly Svetlana, Bakogiannis Constantinos, Tousoulis Dimitris, Kessler Benedikt, Casadei Barbara, Channon Keith M, Antoniades Charalambos

Abstract excerpt

Oxidative stress plays a critical role in the vascular complications of type 2 diabetes. We examined the effect of type 2 diabetes on NADPH oxidase in human vessels and explored the mechanisms of this interaction. Segments of internal mammary arteries (IMAs) with their perivascular adipose tissue (PVAT) and thoracic adipose tissue were obtained from 386 patients undergoing coronary bypass surgery (127 with type 2...

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PMID: 25552596
DOI: 10.2337/db14-1011

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ADIPOQ

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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