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Article

Design of glycoconjugate vaccines against invasive African Salmonella enterica serovar Typhimurium.

Infection and immunity - 1 Mar 2015

Rondini S, Micoli F, Lanzilao L, Gavini M, Alfini R, Brandt C, Clare S, Mastroeni P, Saul A, MacLennan C A

Abstract excerpt

Nontyphoidal salmonellae, particularly Salmonella enterica serovar Typhimurium, are a major cause of invasive disease in Africa, affecting mainly young children and HIV-infected individuals. Glycoconjugate vaccines provide a safe and reliable strategy against invasive polysaccharide-encapsulated pathogens, and lipopolysaccharide (LPS) is a target of protective immune responses. With the aim of designing an...

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Identifiers

PMID: 25547792
DOI: 10.1128/IAI.03079-14
PMCID: PMC4333450

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