Article
Hyper-IgE syndrome with a novel STAT3 mutation-a single center study from India.
Asian Pacific journal of allergy and immunology - 1 Dec 2014
Saikia Biman, Suri Deepti, Goel Shubham, Rawat Amit, Minz Ranjana W, Gupta Anju, Sharma Sudha, Ohara Osamu, Imai Kohsuke, Nonoyama Shigeaki, Sehgal Shobha, Singh Surjit
Abstract excerpt
BACKGROUND: Hyper IgE syndrome (HIES) is a rare primary immunodeficiency disorder characterized by the triad of elevated IgE and eosinophilia, eczema and recurrent skin and pulmonary infections. Mutation in the STAT3 gene accounts for majority of the autosomal dominant and sporadic forms of HIES. OBJECTIVE: To report clinical and molecular analyses of patients with Hyper IgE syndrome from a single tertiary care...
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