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Changes in the leukocyte methylome and its effect on cardiovascular-related genes after exercise

25 Dec 2014

Abstract excerpt

Physical exercise has proven cardiovascular benefits, yet there is no clear understanding of the related molecular mechanisms leading to this. Here we determined the beneficial epigenetic effects of exercise after sprint interval training, a form of exercise known to improve cardiometabolic health. We quantified genome-wide leukocyte DNA methylation of 12 healthy young (18-24 yr) men before and after 4 wk (thrice...

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PMID: 25539938
DOI: 10.1152/japplphysiol.00878.2014

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