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Article

The role of the potassium channel gene KCNK2 in major depressive disorder.

Psychiatry research - 28 Feb 2015

Congiu Chiara, Minelli Alessandra, Bonvicini Cristian, Bortolomasi Marco, Sartori Riccardo, Maj Carlo, Scassellati Catia, Maina Giuseppe, Trabucchi Luigi, Segala Matilde, Gennarelli Massimo

Abstract excerpt

Six single nucleotide polymorphisms (SNPs) of the KCNK2 gene were investigated for their association with major depressive disorder (MDD) and treatment efficacy in 590 MDD patients and 441 controls. The A homozygotes of rs10779646 were significantly more frequent in patients than controls whereas G allele of rs7549184 was associated with the presence of psychotic symptoms and the severity of disease. Evaluating...

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Share to Potassium Channels, Tandem Pore Domain

Source

Identifiers

PMID: 25535009
DOI: 10.1016/j.psychres.2014.11.061

Genes

KCNK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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