Magnetic resonance imaging improves breast screening sensitivity in BRCA mutation carriers age ≥ 50 years: evidence from an individual patient data meta-analysis.

doi:10.1200/JCO.2014.56.6232

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Article

Magnetic resonance imaging improves breast screening sensitivity in BRCA mutation carriers age ≥ 50 years: evidence from an individual patient data meta-analysis.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Feb 2015

Phi Xuan-Anh, Houssami Nehmat, Obdeijn Inge-Marie, Warner Ellen, Sardanelli Francesco, Leach Martin O, Riedl Christopher C, Trop Isabelle, Tilanus-Linthorst Madeleine M A, Mandel Rodica, Santoro Filippo, Kwan-Lim Gek, Helbich Thomas H, de Koning Harry J, Van den Heuvel Edwin R, de Bock Geertruida H

Abstract excerpt

PURPOSE: There is no consensus on whether magnetic resonance imaging (MRI) should be included in breast screening protocols for women with BRCA1/2 mutations age ≥ 50 years. Therefore, we investigated the evidence on age-related screening accuracy in women with BRCA1/2 mutations using individual patient data (IPD) meta-analysis. PATIENTS AND METHODS: IPD were pooled from six high-risk screening trials including...

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PMID: 25534390
DOI: 10.1200/JCO.2014.56.6232

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BRCA1

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Magnetic resonance imaging improves breast screening sensitivity in BRCA mutation carriers age ≥ 50 years: evidence from an individual patient data meta-analysis.PMID 25534390Read ↗

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