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Article

Lack of familial aggregation in chronic constipation excluding irritable bowel syndrome: a population-based study.

Digestive diseases and sciences - 1 May 2015

Chang Joseph Y, Locke G Richard, Schleck Cathy D, Zinsmeister Alan R, Talley Nicholas J

Abstract excerpt

BACKGROUND: Despite strong evidence supporting a genetic and gene-environment interaction in the irritable bowel syndrome (IBS), the role of genes and early life in another common functional bowel disorder, chronic constipation (CC), have been little studied. AIM: To determine whether familial aggregation occurs in CC and whether risk factors differed in those with family members. METHODS: A randomly selected...

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Identifiers

PMID: 25532498
DOI: 10.1007/s10620-014-3475-x
PMCID: PMC4526026

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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