Article
Copper isotope effect in serum of cancer patients. A pilot study.
Metallomics : integrated biometal science - 1 Feb 2015
Télouk Philippe, Puisieux Alain, Fujii Toshiyuki, Balter Vincent, Bondanese Victor P, Morel Anne-Pierre, Clapisson Gilles, Lamboux Aline, Albarede Francis
Abstract excerpt
The isotope effect describes mass-dependent variations of natural isotope abundances for a particular element. In this pilot study, we measured the (65)Cu/(63)Cu ratios in the serums of 20 breast and 8 colorectal cancer patients, which correspond to, respectively, 90 and 49 samples taken at different times with molecular biomarker documentation. Copper isotope compositions were determined by multiple-collector...
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