Article
Environmental challenge, epigenetic plasticity and the induction of altered phenotypes in mammals.
Epigenomics - 1 Jan 2014
Lillycrop Karen A, Burdge Graham C
Abstract excerpt
The level of transcriptional activity of a gene is regulated by epigenetic processes. There is compelling evidence that environmental challenges throughout the life course can induce phenotypic change. In this review, we summarize the current evidence, focusing specifically on the effects of nutrition and of environmental pollutants, that epigenetic processes underpin the induction by environmental change of...
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