Article
CYP2C19 genotype and early ischemic lesion recurrence in stroke patients treated with clopidogrel.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association - 1 Feb 2015
Jeong Tae-Dong, Kim Seung Min, Kim Hyo Jin, Lee Woochang, Kwon Sun U, Min Won-Ki, Kang Dong-Wha, Chun Sail
Abstract excerpt
BACKGROUND: Early recurrent ischemic lesions detected on diffusion-weighted imaging (DWI) have been proposed as a surrogate marker for clinical recurrence. We hypothesized that cytochrome P450 2C19 (CYP2C19) genotype influences the incidence of early recurrence on DWI in acute stroke patients treated with clopidogrel. METHODS: We enrolled 76 Korean patients with acute ischemic stroke due to large artery...
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