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Article

Aspirin plus clopidogrel may reduce the risk of early neurologic deterioration in ischemic stroke patients carrying CYP2C19*2 reduced-function alleles.

Journal of neurology - 1 Oct 2018

Yi Xingyang, Zhou Qiang, Wang Chun, Lin Jing, Chai Zhenxiao

Abstract excerpt

OBJECTIVES: The mechanisms of early neurologic deterioration (END) and prevention strategies for END are not completely understood. The aim of this study was to investigate the association between CYP2C19*2 variants and END, and the effectiveness of antiplatelet therapy for prevention of END according to CYP2C19*2 genotypes in patients with ischemic stroke (IS). MATERIALS AND METHODS: This was a two-center,...

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Source

Identifiers

PMID: 30128710
DOI: 10.1007/s00415-018-8998-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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