Article
Brief Report: Phenotypic Differences and their Relationship to Paternal Age and Gender in Autism Spectrum Disorder.
Journal of autism and developmental disorders - 1 Jun 2015
Vierck Esther, Silverman Jeremy M
Abstract excerpt
Two modes of inheritance have been proposed in autism spectrum disorder, transmission though pre-existing variants and de novo mutations. Different modes may lead to different symptom expressions in affected individuals. De novo mutations become more likely with advancing paternal age suggesting...
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