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Article

IDH1/2 mutation is associated with seizure as an initial symptom in low-grade glioma: A report of 311 Chinese adult glioma patients.

Epilepsy research - 1 Jan 2015

Zhong Zhang, Wang Zheng, Wang Yinyan, You Gan, Jiang Tao

Abstract excerpt

BACKGROUND: Seizure commonly presents as an initial symptom and plays an important role in the clinical presentation and quality of life of patients with low-grade glioma (LGG). To date, the mechanism and genetic alterations underlying tumor-related seizures in LGG remain to be fully elucidated. Both isocitrate dehydrogenase 1/2 (IDH1/2) mutation and seizure frequently occur in patients with LGG. We set out to...

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Brain Neoplasms
Follow-Up Studies
Glioma
Isocitrate Dehydrogenase
Logistic Models

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Multivariate Analysis

Neoplasm Grading

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PMID: 25524848
DOI: 10.1016/j.eplepsyres.2014.09.012

Genes

IDH1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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