Article
Dissemination of cephalosporin resistance genes between Escherichia coli strains from farm animals and humans by specific plasmid lineages.
PLoS genetics - 1 Dec 2014
de Been Mark, Lanza Val F, de Toro María, Scharringa Jelle, Dohmen Wietske, Du Yu, Hu Juan, Lei Ying, Li Ning, Tooming-Klunderud Ave, Heederik Dick J J, Fluit Ad C, Bonten Marc J M, Willems Rob J L, de la Cruz Fernando, van Schaik Willem
Abstract excerpt
Third-generation cephalosporins are a class of β-lactam antibiotics that are often used for the treatment of human infections caused by Gram-negative bacteria, especially Escherichia coli. Worryingly, the incidence of human infections caused by third-generation cephalosporin-resistant E. coli is increasing worldwide. Recent studies have suggested that these E. coli strains, and their antibiotic resistance genes,...
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