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Exploration of the genomic diversity of third-generation cephalosporin-resistant Escherichia coli in Australian clinical settings.

Microbial genomics - 1 Jan 2026

Maqbool Munazzah, Sherry Norelle L, Kwong Jason C, Howden Benjamin P, Gorrie Claire L, Ingle Danielle J, The Controlling Superbugs Study Group

Abstract excerpt

Escherichia coli resistant to third-generation cephalosporins (3GCs) is a WHO priority pathogen due to its antimicrobial resistance (AMR). In high-income countries, such as Australia, 3GC-resistant E. coli are a common cause of extra-intestinal infections in both healthcare and community settings. Long-term targeted surveillance efforts of AMR in E. coli routinely identify E. coli as a leading pathogen in...

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PMID: 41528337
DOI: 10.1099/mgen.0.001554
PMCID: PMC12799292

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