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Article

[Biochemical abnormality of mutant TDP-43 protein].

Rinsho shinkeigaku = Clinical neurology - 1 Jan 2014

Yamanaka Koji

Abstract excerpt

Dominant mutations in the TDP-43 gene are causative for familial ALS, however, the relationship between mutant protein biochemical phenotypes and disease course and their significance to disease pathomechanism are unclarified. We found that longer half-lives of mutant proteins correlated with acc...

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PMID: 25519967
DOI: 10.5692/clinicalneurol.54.1148

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25519967-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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