Article
[Biochip for determination of genetic markers of sporadic Alzheimer's disease in the Russian Slavic population].
Molekuliarnaia biologiia - 1 Jan 2000
Nizamutdinov I I, Andreeva T V, Stepanov V A, Marusin A V, Rogaev E I, Zasedatelev A S, Nasedkina T V
Abstract excerpt
A biological microchip (biochip) for the genetic predis- position to sporadic form of Alzheimer's disease studying has been developed. The biochip allows determina- tion of ten genetic polymorphisms within APOE, TOMM40, APOJ, EXOC3L2, GAB2, A2M, CR1, BIN1 and PICALM genes. The genotyping assay includes the amplification of loci of interest and further allele-specific hybridization of the fluorescent labeled...
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