Use of Highly Pathogenic Avian Influenza A(H5N1) Gain-Of-Function Studies for Molecular-Based Surveillance and Pandemic Preparedness

Abstract excerpt

Zoonotic influenza viruses circulating in poultry and swinepose an ever present threat to human health. In particular, the rapid geographical expansion of highly pathogenic avian influ-enza (HPAI) A(H5N1) throughout Asia and then into Europe, the Middle East, and Africa during the 2000s galvanized the global community in an attempt to control this rapidly growing threat. Despite successful control efforts in some...

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