Article
Slit molecules prevent entrance of trunk neural crest cells in developing gut.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience - 1 Apr 2015
Zuhdi Nora, Ortega Blanca, Giovannone Dion, Ra Hannah, Reyes Michelle, Asención Viviana, McNicoll Ian, Ma Le, de Bellard Maria Elena
Abstract excerpt
Neural crest cells emerge from the dorsal neural tube early in development and give rise to sensory and sympathetic ganglia, adrenal cells, teeth, melanocytes and especially enteric nervous system. Several inhibitory molecules have been shown to play important roles in neural crest migration, among them are the chemorepulsive Slit1-3. It was known that Slits chemorepellants are expressed at the entry to the gut,...
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