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Article

Developmental determinants of the independence and complexity of the enteric nervous system.

Trends in neurosciences - 1 Oct 2010

Gershon Michael D

Abstract excerpt

Enteric nervous system (ENS) development is relevant to Hirschsprung's disease (HSCR; congenital aganglionosis of the terminal bowel), which is still imperfectly treated. Mutations in genes encoding the RET receptor tyrosine kinase and endothelin receptor type B (EDNRB) are involved in HSCR pathogenesis; however, also important in ENS development are molecules that mediate events that are more restricted than...

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Source

Identifiers

PMID: 20633936
DOI: 10.1016/j.tins.2010.06.002

Genes

EDNRB
RET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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