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Article

Ets and GATA transcription factors play a critical role in PMA-mediated repression of the ckβ promoter via the protein kinase C signaling pathway.

PloS one - 1 Jan 2014

Kuan Chee Sian, Yee Yoke Hiang, See Too Wei Cun, Few Ling Ling

Abstract excerpt

BACKGROUND: Choline kinase is the most upstream enzyme in the CDP-choline pathway. It catalyzes the phosphorylation of choline to phosphorylcholine in the presence of ATP and Mg2+ during the biosynthesis of phosphatidylcholine, the major phospholipid in eukaryotic cell membranes. In humans, choline kinase (CK) is encoded by two separate genes, ckα and ckβ, which produce three isoforms, CKα1, CKα2, and CKβ....

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Identifiers

PMID: 25490397
DOI: 10.1371/journal.pone.0113485
PMCID: PMC4260826

Genes

GATA2
GATA3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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