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Article

Role of the pro-survival molecule Bfl-1 in melanoma.

The international journal of biochemistry & cell biology - 1 Feb 2015

Hind C K, Carter M J, Harris C L, Chan H T C, James S, Cragg M S

Abstract excerpt

Bfl-1 is a pro-survival Bcl-2 family member overexpressed in a subset of chemoresistant tumours, including melanoma. Here, we characterised the expression and regulation of Bfl-1 in normal and malignant melanocytes and determined its role in protecting these cells from chemotherapy-induced apopto...

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Source

Identifiers

PMID: 25486183
DOI: 10.1016/j.biocel.2014.11.015

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25486183-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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