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Article

zen and the art of phenotypic maintenance: canalization of embryonic dorsal-ventral patterning in Drosophila.

Fly - 1 Jan 2014

Gavin-Smyth Jackie, Ferguson Edwin L

Abstract excerpt

We recently uncovered a novel genetic mechanism that generates the phenotypic uniformity, or canalization, of BMP signaling and cell fate specification during patterning of the dorsal-ventral (D/V) axis in D. melanogaster embryos. We went on to show that other wild-type Drosophila species lack this canalizing genetic circuitry and, consequently, have non-robust D/V patterning. In this review, we propose molecular...

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Identifiers

PMID: 25482877
DOI: 10.4161/19336934.2014.983385
PMCID: PMC4594538

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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